Thionyl Chloride → 2-Methyl-3-hydroxy-4-chloromethyl-5-vinylpyridine hydrochloride
反応式
[ClH:1].[CH3:2][C:3]1[C:8]([OH:9])=[C:7]([CH2:10]O)[C:6]([CH:12]=[CH2:13])=[CH:5][N:4]=1.S(Cl)([Cl:16])=O>O1CCCC1>[ClH:16].[CH3:2][C:3]1[C:8]([OH:9])=[C:7]([CH2:10][Cl:1])[C:6]([CH:12]=[CH2:13])=[CH:5][N:4]=1参加物
4
実験手順
A mixture of 1.65 g. of 2-methyl-3-hydroxy-4-hydroxymethyl-5-vinylpyridine hydrochloride, 1 ml. of thionyl chloride and 20 ml. of tetrahydrofuran is refluxed 6 hours. After cooling, the precipitate is collected on a filter, washed with ether and dried to give 2-methyl-3-hydroxy-4-chloromethyl-5-vinyl pyridine hydrochloride.
後処理
- additionA mixture of 1.65 g
- temperatureAfter cooling
- customthe precipitate is collected on a filter
- washwashed with ether
- customdried
出典と根拠
- ORDレコード
- ord-dae7d52e713845bea7f43d91efd3444f
- 出典データセット
- uspto-grants-1979_03
- 特許番号
- US04144342
反応ノート
読み込み中…