Ammonia → 2-(Amino(methylthio)methylene)malononitrile
反応式
N.[C:2]([C:4](=[C:7](SC)[S:8][CH3:9])[C:5]#[N:6])#[N:3].CS.C(#[N:17])C=C>C(O)C>[NH2:17][C:7]([S:8][CH3:9])=[C:4]([C:5]#[N:6])[C:2]#[N:3]参加物
6
実験手順
Two liters of ethanol were saturated with ammonia gas at 15°. At ambient temperature, 278.3 g of 2-cyano-3,3-bis(methylthio)propenenitrile were added portionwise. A sodium hydroxide trap was used to trap the methyl mercaptan by-product. After complete addition of the propenenitrile the reaction mixture was cooled to approximately 10°. The solid which separated was collected by filtration and washed with cold ethanol to give, after drying, 206.3 g of white 3-amino-2-cyano-3-(methylthio)propenenitrile, m.p. 228°-230°. The nmr was consistent with the assigned structure.
後処理
- customA sodium hydroxide trap was used to trap
- temperaturewas cooled to approximately 10°
- customThe solid which separated
- filtrationwas collected by filtration
- washwashed with cold ethanol
- customto give
- customafter drying
出典と根拠
- ORDレコード
- ord-ff596e9f27bf4f31a60fdb7b1c4ade32
- 出典データセット
- uspto-grants-1978_02
- 特許番号
- US04075001
反応ノート
読み込み中…