Acetonitrile → Hydrazinecarboxylic acid, 2-(phenylacetyl)-, methyl ester
反応式
[C:1]([O:5][CH3:6])(=[O:4])[NH:2][NH2:3].C(#N)C.[C:10]1([CH2:16][C:17](Cl)=[O:18])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>O>[C:10]1([CH2:16][C:17]([NH:3][NH:2][C:1]([O:5][CH3:6])=[O:4])=[O:18])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1参加物
5
実験手順
To a solution of 90.1 g. (1.0 mole) of methyl carbazate and 500 ml. of acetonitrile 154.6 g. (1.0 mole) of phenyl acetyl chloride are added. The reaction mixture is heated to boiling for 15 hours and clarified. The residual oil is poured into 500 ml. of water, whereby the oil soon solidifies. Thus 158.4 g. of the white desired compound are obtained, yield 76.1%, m.p.: 94°-95° C.
後処理
- temperatureThe reaction mixture is heated
- additionThe residual oil is poured into 500 ml
出典と根拠
- ORDレコード
- ord-c4d366d16fad4addb4c1a848f03a9d86
- 出典データセット
- uspto-grants-1989_04
- 特許番号
- US04824670
反応ノート
読み込み中…