Water → Bromoethynyl triisopropylsilane

HRID 623671

反応式

HRID 623671 の反応式
C1C(=O)N([Br:8])C(=O)C1.[CH:9]([Si:12]([C:19]#[CH:20])([CH:16]([CH3:18])[CH3:17])[CH:13]([CH3:15])[CH3:14])([CH3:11])[CH3:10].CCCCC.O>CC(C)=O.[N+]([O-])([O-])=O.[Ag+]>[Br:8][C:20]#[C:19][Si:12]([CH:13]([CH3:14])[CH3:15])([CH:9]([CH3:11])[CH3:10])[CH:16]([CH3:18])[CH3:17]

参加物

7

反応物 4

HCID 962WaterHCID 8003PentaneHCID 67184N-bromobutanimideHCID 2734682(Triisopropylsilyl)acetylene

生成物 1

HCID 11196280Bromoethynyl triisopropylsilane

試薬・触媒・溶媒 2

HCID 24470Silver Nitrate触媒HCID 180Acetone溶媒

実験手順

NBS (2.14 g, 12 mmol) and AgNO3 (170 mg, 1 mmol) were added to a solution of triisopropylsilylacetylene (2.24 ml, 10 mmol) in acetone (15 ml). The solution was stirred for 2 hours at RT. Pentane (20 ml) and H2O (20 ml) were added and the solution was stirred for 30 minutes. The organic phase was extracted with pentane (3×20 ml) and dried over Na2SO4. The solvent was removed under reduced pressure at RT and the residue was used in the next reaction without any purification.

後処理

  1. stirringthe solution was stirred for 30 minutes
  2. extractionThe organic phase was extracted with pentane (3×20 ml)
  3. dry with materialdried over Na2SO4
  4. customThe solvent was removed under reduced pressure at RT
  5. customthe residue was used in the next reaction without any purification

出典と根拠

ORDレコード
ord-087145f8e7ff4a7eb7f1c6f990882090
出典データセット
uspto-grants-2016_04
特許番号
US09302998B2

関連ノート

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