2-[(2-Nitrophenyl)sulfanyl]benzoic acid → 2-((2-Aminophenyl)thio)benzoic acid

HRID 625174

反応式

HRID 625174 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10][C:11]1[CH:19]=[CH:18][CH:17]=[CH:16][C:12]=1[C:13]([OH:15])=[O:14])([O-])=O>C(OCC)(=O)C.[Pd]>[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10][C:11]1[CH:19]=[CH:18][CH:17]=[CH:16][C:12]=1[C:13]([OH:15])=[O:14]

参加物

4

反応物 1

HCID 3769782-[(2-Nitrophenyl)sulfanyl]benzoic acid

生成物 1

HCID 109558282-((2-Aminophenyl)thio)benzoic acid

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

To a solution of 2-((2-nitrophenyl)thio)benzoic acid, prepared as described in the previous step, (43.3 g, 0.157 mol) in ethyl acetate (500 mL) was added Pd/C (8 g). The reaction solution was stirred at room temperature overnight under hydrogen gas atmosphere. The mixture was filtered and concentrated to provide the title compound.

後処理

  1. filtrationThe mixture was filtered
  2. concentrationconcentrated

出典と根拠

ORDレコード
ord-91e47b447afe49b2be3082fc09c284fa
出典データセット
uspto-grants-2016_04
特許番号
US09304126B2

関連ノート

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