反応式
[Br:1][C:2]1[CH:3]=[C:4]([CH:7]=[O:8])[S:5][CH:6]=1.[CH3:9][C:10]#[N:11]>>[Br:1][C:2]1[CH:3]=[C:4]([CH:7]([OH:8])[CH2:9][C:10]#[N:11])[S:5][CH:6]=1参加物
3
実験手順
Addition of CH3CN to 4-bromothiophene-2-carbaldehyde following the method used in Example 2 gave 3-(4-bromothiophen-2-yl)-3-hydroxypropanenitrile as a light brown oil which was used in the next step without additional purification. Yield (1.95 g, 80%).
出典と根拠
- ORDレコード
- ord-0b4c34a7edb944d7980955e9f1862dbf
- 出典データセット
- uspto-grants-2016_09
- 特許番号
- US09447078B2
関連ノート
読み込み中…