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llms.txt · MCPガイドプライバシーポリシー · 利用規約 · サポートv1.8.0
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Methanol → Diisopropyl fumarate cinnamic acid

HRID 634039
ノート
印刷プレビュー

反応式

HRID 634039 の反応式
[C:1]([O:11][CH:12]([CH3:14])[CH3:13])(=[O:10])/[CH:2]=[CH:3]/[C:4]([O:6][CH:7]([CH3:9])[CH3:8])=[O:5].[C:15]([OH:25])(=[O:24])[CH:16]=[CH:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.CO>O1CCCC1.C(OOC(C)(C)C)(=O)C(C)(C)C>[C:4]([O:6][CH:7]([CH3:9])[CH3:8])(=[O:5])/[CH:3]=[CH:2]/[C:1]([O:11][CH:12]([CH3:14])[CH3:13])=[O:10].[C:15]([OH:25])(=[O:24])[CH:16]=[CH:17][C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1
参加物実験手順後処理出典と根拠反応ノート

参加物

6

反応物 3

HCID 887MethanolHCID 87842-Propenoic acid, 3-phenyl-HCID 5357078Diisopropyl fumarate

生成物 1

HCID 118090912Diisopropyl fumarate cinnamic acid収率 463.7%

試薬・触媒・溶媒 2

HCID 61238tert-BUTYL PEROXYPIVALATE触媒HCID 8028Tetrahydrofuran
溶媒

実験手順

A glass ampule having a volume of 75 mL was charged with 50 g (0.25 mol) of diisopropyl fumarate, 1.9 g (0.013 mol) of cinnamic acid and 0.29 g (0.0016 mol) of tert-butyl peroxypivalate as a polymerization initiator and after repeating purging with nitrogen and release of the pressure, sealed in the pressure-reduced state. This ampule was placed in a constant temperature bath at 50° C. and held for 48 hours, thereby performing radical polymerization. After the completion of polymerization reaction, the polymerization product was taken out of the ampule and dissolved in 400 g of tetrahydrofuran. The resulting polymer solution was added dropwise, for precipitation, to 3 L of methanol, and the precipitate was vacuum-dried at 80° C. for 10 hours to obtain 21 g of a diisopropyl fumarate/cinnamic acid copolymer (yield: 41%).

後処理

  1. customafter repeating purging with nitrogen and release of the pressure
  2. customsealed in the pressure-reduced state
  3. customThis ampule was placed in a constant temperature bath at 50° C.
  4. custompolymerization
  5. customAfter the completion of polymerization reaction
  6. customthe precipitate was vacuum-dried at 80° C. for 10 hours

出典と根拠

ORDレコード
ord-244446f0565748fa97bfdd5e1da13c1e
出典データセット
uspto-grants-2016_04
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US09321870B2

反応ノート

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