Sodium Hydroxide → L-Leucine
反応式
C([NH:4][C@H:5]([C:10]([OH:12])=[O:11])[CH2:6][CH:7]([CH3:9])[CH3:8])(=O)C.C(N[C@H](C(O)=O)[C@H](CC)C)(=O)C.[OH-].[Na+]>O>[NH2:4][C@H:5]([C:10]([OH:12])=[O:11])[CH2:6][CH:7]([CH3:9])[CH3:8]参加物
5
反応条件
- 温度
- 36 °C
実験手順
86.6 grams of this mixture of equal parts of N-acetyl-leucine and N-acetyl-isoleucine were suspended in 400 ml of water and adjusted to pH 7.0 with 50% aqueous sodium hydroxide. There were added 50 mg of CoCl2X6H2O and 50 mg of commerical pig kidney acylase (1200 U/mg) and the mixture was filled up to 500 ml with water. The clear solution was stirred at 36° C. for 6 hours. By filtering with suction, washing and drying there were obtained 17.9 grams of pure L-leucine having a rotary value of [α]D25 =+15.9°.
後処理
- additionThere were added 50 mg of CoCl2X6H2O and 50 mg of commerical pig kidney acylase (1200 U/mg)
- filtrationBy filtering with suction
- washwashing
- customdrying there
出典と根拠
- ORDレコード
- ord-1d3a85980dba4ee1a0ce9052fe130086
- 出典データセット
- uspto-grants-1985_12
- 特許番号
- US04562153
反応ノート
読み込み中…