Water → 4-Chloro-1-(4-chloro-2-methylphenoxy)-2-butanol

HRID 64691

反応式

HRID 64691 の反応式
[CH3:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[OH:9].Cl[CH2:11][CH:12]([OH:16])[CH2:13][CH2:14][Cl:15].[OH-].[Na+].O>C(O)(C)(C)C>[Cl:15][CH2:14][CH2:13][CH:12]([OH:16])[CH2:11][O:9][C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[CH3:1]

参加物

6

反応物 4

HCID 962WaterHCID 14798Sodium HydroxideHCID 148554-Chloro-2-methylphenolHCID 170211,4-Dichloro-2-butanol

生成物 1

HCID 131203464-Chloro-1-(4-chloro-2-methylphenoxy)-2-butanol

試薬・触媒・溶媒 1

HCID 6386tert-Butanol溶媒

実験手順

4-Chloro-1-(4-chloro-2-methylphenoxy)-2-butanol was prepared according to the procedure of Preparation 4 using 105 g. (0.74 mole) of 2-methyl-4-chlorophenol, 171.5 g. (1.2 mole) of 1,4-dichloro-2-butanol, 50.3 g. of sodium hydroxide, 300 ml. of water and 300 ml. of tertiary butanol. There was obtained 84 g. (45.5%) of product which distilled at 135° C./0.01 mm.

後処理

  1. customaccording to the procedure of Preparation 4 using 105 g
  2. customThere was obtained 84 g
  3. distillation(45.5%) of product which distilled at 135° C./0.01 mm

出典と根拠

ORDレコード
ord-008d879749ca4fe7974966c270b01e5d
出典データセット
uspto-grants-1986_09
特許番号
US04609735

関連ノート

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