Methomyl → Methyl N-[[[[[(diethoxyphosphinothioyl)isopropylamino]sulfinyl]methylamino]carbonyl]oxy]ethanimidothioate

HRID 647790

反応式

HRID 647790 の反応式
[CH3:1][NH:2][C:3]([O:5][N:6]=[C:7]([S:9][CH3:10])[CH3:8])=[O:4].[S:11](Cl)(Cl)=[O:12].[CH:15]([NH:18][P:19](=[S:26])([O:23][CH2:24][CH3:25])[O:20][CH2:21][CH3:22])([CH3:17])[CH3:16]>N1C=CC=CC=1>[CH2:21]([O:20][P:19]([N:18]([CH:15]([CH3:17])[CH3:16])[S:11]([CH2:1][NH:2][C:3]([O:5][N:6]=[C:7]([S:9][CH3:10])[CH3:8])=[O:4])=[O:12])([O:23][CH2:24][CH3:25])=[S:26])[CH3:22]

参加物

5

反応物 3

HCID 4109MethomylHCID 24386Thionyl ChlorideHCID 778771Phosphoramidothioic acid, (1-methylethyl)-, O,O-diethyl ester

生成物 1

HCID 86739075Methyl N-[[[[[(diethoxyphosphinothioyl)isopropylamino]sulfinyl]methylamino]carbonyl]oxy]ethanimidothioate

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

Methyl N-[[[[[(diethoxyphosphinothioyl)isopropylamino]sulfinyl]methylamino]carbonyl]oxy]ethanimidothioate was prepared by the procedure employed in Example 9, by reacting methyl N-[[(methylamino)carbonyl]oxy]ethanimidothioate (2.43 g, 0.015 mole), thionyl chloride (1.79 g, 0.015 mole), and O,O-diethyl isopropylphosphoramidothioate (3.17 g, 0.015 mole) in pyridine (10 ml). Recrystallization from cyclohexane afforded 1.73 g of colorless prisms of the formula below, mp 53~54°. ##STR27##

後処理

  1. customRecrystallization from cyclohexane

出典と根拠

ORDレコード
ord-3e83de3531d44c178b3cdf45483ba5d4
出典データセット
uspto-grants-1983_10
特許番号
US04410518

関連ノート

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