Methomyl → Methyl N-[[[[[(diethoxyphosphinothioyl)cyclopentylamino]sulfinyl]methylamino]carbonyl]oxy]ethanimidothioate

HRID 647791

反応式

HRID 647791 の反応式
[CH3:1][NH:2][C:3]([O:5][N:6]=[C:7]([S:9][CH3:10])[CH3:8])=[O:4].[S:11](Cl)(Cl)=[O:12].[CH:15]1([NH:20][P:21](=[S:28])([O:25][CH2:26][CH3:27])[O:22][CH2:23][CH3:24])[CH2:19][CH2:18][CH2:17][CH2:16]1>N1C=CC=CC=1>[CH2:23]([O:22][P:21]([N:20]([CH:15]1[CH2:16][CH2:17][CH2:18][CH2:19]1)[S:11]([CH2:1][NH:2][C:3]([O:5][N:6]=[C:7]([S:9][CH3:10])[CH3:8])=[O:4])=[O:12])([O:25][CH2:26][CH3:27])=[S:28])[CH3:24]

参加物

5

反応物 3

HCID 4109MethomylHCID 24386Thionyl ChlorideHCID 20483188O,O-diethyl cyclopentylphosphoramidothioate

生成物 1

HCID 86739076Methyl N-[[[[[(diethoxyphosphinothioyl)cyclopentylamino]sulfinyl]methylamino]carbonyl]oxy]ethanimidothioate

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

Methyl N-[[[[[(diethoxyphosphinothioyl)cyclopentylamino]sulfinyl]methylamino]carbonyl]oxy]ethanimidothioate was prepared by the procedure employed in Example 9, by reaching methyl N-[[(methylamino)carbonyl]oxy]ethanimidothioate (2.43 g, 0.015 mole), thionyl chloride (1.79 g, 0.015 mole) and O,O-diethyl cyclopentylphosphoramidothioate (3.56 g, 0.015 mole) in pyridine. Recrystallization from cyclohexane afforded 1.0 g of colorless prisms of the formula below, mp 79~80°. ##STR29##

後処理

  1. customRecrystallization from cyclohexane

出典と根拠

ORDレコード
ord-85eb3944d4da459d81838a7c6ac81cb5
出典データセット
uspto-grants-1983_10
特許番号
US04410518

関連ノート

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