Water → 2-Chloro-2,4,4-trimethylpentane
反応式
[CH3:1][C:2]([CH2:4][C:5]([CH3:8])([CH3:7])[CH3:6])=[CH2:3].S(Cl)([Cl:11])=O.O>C(Cl)Cl>[Cl:11][C:2]([CH3:1])([CH2:4][C:5]([CH3:8])([CH3:7])[CH3:6])[CH3:3]参加物
5
反応条件
- 温度
- -30 °C
実験手順
15 ml of 2,4,4-trimethyl-pentene-1 are dissolved in 150 ml of CH2Cl2, cooled to -30° C. and mixed dropwise with a mixture of 10.3 ml of thionyl chloride and 5.4 ml of H2O. The mixture is then heated to 0° C. and washed after 2.5 hours with cold 1% aqueous K2CO3 solution, then with ice-cold water. The product is dried over MgSO4 and distilled off. Yield 85%; nD20 =1.4308; Bpt.10 mm 38° C.
後処理
- temperatureThe mixture is then heated to 0° C.
- washwashed after 2.5 hours with cold 1% aqueous K2CO3 solution
- dry with materialThe product is dried over MgSO4
- distillationdistilled off
- custom10 mm 38° C.
出典と根拠
- ORDレコード
- ord-430db93bb1604512ad66e62ccbabb9cf
- 出典データセット
- uspto-grants-1986_09
- 特許番号
- US04611037
反応ノート
読み込み中…