Hydrogen Peroxide → 28893-44-9

HRID 651944

反応式

HRID 651944 の反応式
[CH3:1][CH:2]([CH2:4][CH2:5][CH2:6][C@H:7]([C@@H:9]1[C@:26]2([CH3:27])[C@H:12]([C@H:13]3[C@H:23]([CH2:24][CH2:25]2)[C@:21]2([CH3:22])[C:16](=[CH:17][C:18](=[O:28])[CH:19]=[CH:20]2)[CH:15]=[CH:14]3)[CH2:11][CH2:10]1)[CH3:8])[CH3:3].[OH-:29].[Na+].OO>C(O)C>[O:29]1[C@H:19]2[C:18](=[O:28])[CH:17]=[C:16]3[C@:21]([CH3:22])([C@@H:20]12)[C@@H:23]1[C@H:13]([C@H:12]2[C@:26]([CH3:27])([CH2:25][CH2:24]1)[C@@H:9]([C@H:7]([CH3:8])[CH2:6][CH2:5][CH2:4][CH:2]([CH3:1])[CH3:3])[CH2:10][CH2:11]2)[CH:14]=[CH:15]3

参加物

5

反応物 3

HCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 1073901,4,6-Cholestatrien-3-one

生成物 1

HCID 1391110828893-44-9

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

The trienone from (a) (1 gm) in ethanol (50 mls) at 0° was treated with 10% aqueous sodium hydroxide (0.25 ml) and 30% aqueous H2O2 (2.5 ml). The mixture was stored at 5° overnight and then the resulting epoxide was filtered off, washed with aqueous alcohol and dried to afford the title compound (0.86 mgs). Recrystallization from ethanol gave colourless needles, melting point 107°-109°.

後処理

  1. filtrationthe resulting epoxide was filtered off
  2. washwashed with aqueous alcohol
  3. customdried

出典と根拠

ORDレコード
ord-b723e16e0e7c40a996b359e9ea7317d4
出典データセット
uspto-grants-1987_06
特許番号
US04670190

関連ノート

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