Benzaldehyde → 5-Benzylidenehydantoin

HRID 652564

反応式

HRID 652564 の反応式
NCC(O)=O.C(=O)([O-])[O-].[Na+].[Na+].[CH:12](=O)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[NH:20]1[CH2:26][C:24](=[O:25])[NH:23][C:21]1=[O:22]>O>[CH:12](=[C:26]1[NH:20][C:21](=[O:22])[NH:23][C:24]1=[O:25])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

参加物

6

反応物 4

HCID 240BenzaldehydeHCID 750GlycineHCID 10006HydantoinHCID 10340Sodium Carbonate

生成物 1

HCID 978575-Benzylidenehydantoin収率 88.3%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A 37.5 g amount of glycine and 26.5 g of sodium carbonate were dissolved in 200 ml of water in the flask. Then, 53.0 g of benzaldehyde and 50.0 g of hydantoin were added to the resultant solution. The mixture was allowed to react at a temperature of 100° C. for 1 hour while stirring. During the reaction, the pH of the reaction mixture was 9.7 to 9.4. After cooling, the precipitated 5-benzylidene hydantoin was separated and recovered from the reaction mixture. Thus, 83.0 g of 5-benzylidene hydantoin was obtained. The yield was 88% based on the hydantoin.

後処理

  1. customto react at a temperature of 100° C. for 1 hour
  2. customDuring the reaction
  3. temperatureAfter cooling
  4. customthe precipitated 5-benzylidene hydantoin was separated
  5. customrecovered from the reaction mixture

出典と根拠

ORDレコード
ord-c90b895d8587415dabf3dde44a8eac9d
出典データセット
uspto-grants-1987_06
特許番号
US04672127

関連ノート

読み込み中…