Glycol monoethyl ether → N-methylanthranilic acid nickel

HRID 652709

反応式

HRID 652709 の反応式
C([O-])(=O)C.[Ni+2:5].C([O-])(=O)C.CCOCCO.[CH3:16][NH:17][C:18]1[C:19](=[CH:23][CH:24]=[CH:25][CH:26]=1)[C:20]([OH:22])=[O:21]>O>[Ni:5].[CH3:16][NH:17][C:18]1[C:19](=[CH:23][CH:24]=[CH:25][CH:26]=1)[C:20]([OH:22])=[O:21]

参加物

5

反応物 3

HCID 8076Glycol monoethyl etherHCID 9756Nickel AcetateHCID 67069N-Methylanthranilic acid

生成物 1

HCID 86741584N-methylanthranilic acid nickel収率 138.2%

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
50 °C

実験手順

23.8 g (0.1 mol) of nickel acetate was added to 500 ml of ethyl cellosolve and stirred. The mixture was heated to 50° C., and 30.2 g (0.2 mol) of N-methyl-anthranilic acid was gradually added. The mixture was subjected to reaction for 2 hours at about 130° C. under refluxing and then dispersed in 2 liters of water. After 1 hour, the dispersion was subjected to filtration and the precipitate was washed with water until neutrality. The precipitate was then dried at 90° C. to obtain about 29 g of pale blue powder.

後処理

  1. customThe mixture was subjected to reaction for 2 hours at about 130° C.
  2. temperatureunder refluxing
  3. filtrationthe dispersion was subjected to filtration
  4. washthe precipitate was washed with water until neutrality
  5. customThe precipitate was then dried at 90° C.

出典と根拠

ORDレコード
ord-12a820d4ef814cc28280da2d675a0e64
出典データセット
uspto-grants-1987_06
特許番号
US04673631

関連ノート

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