Hydroxyamine hydrochloride → HCID 136393678、化合物

HRID 652842ノート

反応式

HRID 652842 の反応式
[Cl:1][C:2]1[C:15]([Cl:16])=[C:14]([OH:17])[CH:13]=[CH:12][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=O.Cl.[NH2:19][OH:20]>N1C=CC=CC=1>[Cl:1][C:2]1[C:15]([Cl:16])=[C:14]([OH:17])[CH:13]=[CH:12][C:3]=1[C:4](=[N:19][OH:20])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

参加物

4

反応物 2

HCID 443297Hydroxyamine hydrochlorideHCID 14009997(2,3-Dichloro-4-hydroxyphenyl)(phenyl)methanone

生成物 1

HCID 136393678HCID 136393678、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

A solution of 18.0 g of 2,3-dichloro-4-hydroxybenzophenone and 9.3 g of hydroxylamine hydrochloride in 100 ml of pyridine is refluxed for 2 hours. Thereafter, the pyridine is evaporated under vacuum and the residual liquid is partitioned between 5% hydrochloric acid and ethyl acetate. The ethylacetate extract is washed with water, dried, and evaporated to give 2,3-dichloro-4-hydroxy-benzophenone oxime.

後処理

  1. customThereafter, the pyridine is evaporated under vacuum
  2. customthe residual liquid is partitioned between 5% hydrochloric acid and ethyl acetate
  3. extractionThe ethylacetate extract
  4. washis washed with water
  5. customdried
  6. customevaporated

出典と根拠

ORDレコード
ord-6f02e04d363742f19abd1a1c2261cdb1
出典データセット
uspto-grants-1987_06
特許番号
US04673746

反応ノート

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