Sodium Hydroxide → Acifluorfen sodium

HRID 65331

反応式

HRID 65331 の反応式
[Cl:1][C:2]1[CH:20]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:14]([O-:16])=[O:15])=[C:9]([CH:13]=1)[C:10]([OH:12])=[O:11].[OH-].[Na+:26]>CO>[Cl:1][C:2]1[CH:20]=[C:19]([C:21]([F:22])([F:23])[F:24])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:14]([O-:16])=[O:15])=[C:9]([CH:13]=1)[C:10]([O-:12])=[O:11].[Na+:26]

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 44073Acifluorfen

生成物 1

HCID 44072Acifluorfen sodium収率 105.4%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid (1.7 g, 0.0047 mole) is dissolved in methanol (25 ml) and sodium hydroxide (4.7 ml of 1N NaOH in methanol, 0.0047 mole) is added rapidly. The solvent is then removed in vacuo to give 1.9 g of product that decomposes at 217° C.

後処理

  1. customThe solvent is then removed in vacuo

出典と根拠

ORDレコード
ord-9e9b4f013e6e41fe8d4ab299c0212c3e
出典データセット
uspto-grants-1986_09
特許番号
US04613360

関連ノート

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