Hydroquinone → N-Octyl-beta-alanine
反応式
[CH2:1]([NH2:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].C1(C=CC(O)=CC=1)O.[C:18]([OH:22])(=[O:21])[CH:19]=[CH2:20].[OH-].[Na+]>CC(C)=O.CO>[CH2:1]([NH:9][CH2:20][CH2:19][C:18]([OH:22])=[O:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]参加物
7
実験手順
To a mixture of n-octylamine (516 g, 4.0 mols), hydroquinone (200 mg) and methanol (400 ml), acrylic acid (144 g, 2.0 mols) was added dropwise with stirring while cooling with ice. After addition, the mixture was refluxed while heating for 4 hours. After cooled to room temperature, NaOH (80 g, 2.0 mols) was added. The reaction mixture was despersed in 6 liters of acetone, and filtration and drying were carried out to obtain the Na salt of N-n-octyl-β-alanine as white crystals having a melting point (dec.) of 242° C. (349 g Yield: 78%).
後処理
- additionwas added dropwise
- temperaturewhile cooling with ice
- additionAfter addition
- temperaturethe mixture was refluxed
- temperaturewhile heating for 4 hours
- filtrationfiltration
- customdrying
出典と根拠
- ORDレコード
- ord-5e8802d8235240cab6cb20b4167dd222
- 出典データセット
- uspto-grants-1986_09
- 特許番号
- US04614699
反応ノート
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