Acetic Acid → 4-Chloro-1-naphthol

HRID 65727

反応式

HRID 65727 の反応式
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([O:12]C)=[CH:4][CH:3]=1.C(O)(=O)C.Br>O>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([OH:12])=[CH:4][CH:3]=1

参加物

5

反応物 3

HCID 176Acetic AcidHCID 260Hydrogen BromideHCID 6060381-Chloro-4-methoxynaphthalene

生成物 1

HCID 117874-Chloro-1-naphthol

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

The known compound 1-chloro-4-methoxynaphthalene is dissolved in 150 ml. of acetic acid and 150 ml. of 48 percent hydrobromic acid, and the mixture is heated at its reflux temperature for 2 hours. The mixture is diluted with 200 ml. of water and cooled to provide 1-chloro-4-hydroxynaphthalene as a crystalline solid.

後処理

  1. temperaturereflux temperature for 2 hours
  2. additionThe mixture is diluted with 200 ml

出典と根拠

ORDレコード
ord-03d39e03caed4569923ddc9bb0d2b986
出典データセット
uspto-grants-1978_12
特許番号
US04128659

関連ノート

読み込み中…