Hydrochloric Acid → 2-Chloro-3-fluoroaniline

HRID 65733

反応式

HRID 65733 の反応式
[Cl:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[N+:9]([O-])=O.Cl.[OH-].[Na+]>>[Cl:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[NH2:9]

参加物

4

反応物 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 888832-Chloro-1-fluoro-3-nitrobenzene

生成物 1

HCID 888842-Chloro-3-fluoroaniline

実験手順

19.6 g. of 2-chloro-3-fluoronitrobenzene (0.11 mole) is reduced with stannous chloride (118 g., 0.63 mole) in 180 ml. of concentrated hydrochloric acid. The solution is basified with aqueous sodium hydroxide and extracted with chloroform to yield 2-chloro-3-fluoroaniline.

後処理

  1. extractionextracted with chloroform

出典と根拠

ORDレコード
ord-1db00a5a9136416fb08e3a530f59cd2f
出典データセット
uspto-grants-1978_12
特許番号
US04128666

関連ノート

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