反応式
[H-].[Na+].Cl[C:4]1[C:5]([CH3:15])=[C:6]([CH3:14])[C:7]2[N:8]([C:10]([NH2:13])=[N:11][N:12]=2)[N:9]=1.[CH2:16]([OH:19])[CH2:17][CH3:18]>CN(C=O)C>[CH3:15][C:5]1[C:4]([O:19][CH2:16][CH2:17][CH3:18])=[N:9][N:8]2[C:10]([NH2:13])=[N:11][N:12]=[C:7]2[C:6]=1[CH3:14]参加物
5
実験手順
1-Propanol (28 ml) was deprotonated analogously to W1.056 with sodium hydride (1.3 g) and reacted with 6-chloro-7,8-dimethyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylamine (W2.006a, 1 g), dissolved in 1-propanol (10 ml) and DMF (10 ml), and worked up. 647 mg of the title compound were isolated in sufficient purity.
出典と根拠
- ORDレコード
- ord-38c169b71e6447ef950376f75ace503a
- 出典データセット
- uspto-grants-2011_12
- 特許番号
- US08076336B2
関連ノート
読み込み中…