Sodium Hydroxide → 5-Phenylfuran-2-carboxylic acid
反応式
[C:1]1([C:7]2[O:11][C:10]([CH:12]=[O:13])=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-:14].[Na+]>[N+]([O-])([O-])=O.[Ag+]>[C:1]1([C:7]2[O:11][C:10]([C:12]([OH:14])=[O:13])=[CH:9][CH:8]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1参加物
4
反応条件
- 温度
- 60 °C
実験手順
To 5-phenyl-2-furaldehyde (35) (690 mg, 4.01 mmol) was added solid NaOH (176 mg, 4.40 mmol) then 10% NaOH solution (6.2 mL). Silver nitrate (680 mg, 4.00 mmol) was added and the reaction mixture heated to 60° C. for 4.5 hours then cooled to ambient temperature. The reaction mixture was then filtered and washed with water. The filtrate was acidified to pH 2 using 2N HCl and the precipitated product filtered and dried to give the title compound.
後処理
- temperaturethen cooled to ambient temperature
- filtrationThe reaction mixture was then filtered
- washwashed with water
- filtrationthe precipitated product filtered
- customdried
出典と根拠
- ORDレコード
- ord-fe5a9621d48b45708e5f897cbdb23907
- 出典データセット
- uspto-grants-2011_12
- 特許番号
- US08080567B2
反応ノート
読み込み中…