Acetone → HCID 178482500、化合物

HRID 67733

反応式

HRID 67733 の反応式
[CH3:1][NH:2][C:3](=[S:6])[NH:4][NH2:5].[CH3:7][C:8]([CH3:10])=O.[F:11][C:12]([F:23])([F:22])[C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][CH:21]=1)[C:16](Cl)=[O:17]>N1C=CC=CC=1>[CH3:7][C:8]1([CH3:10])[S:6][C:3]([NH:2][CH3:1])=[N:4][N:5]1[C:16](=[O:17])[C:15]1[CH:19]=[CH:20][CH:21]=[C:13]([C:12]([F:23])([F:22])[F:11])[CH:14]=1

参加物

5

反応物 3

HCID 180AcetoneHCID 752573-(Trifluoromethyl)benzoyl chlorideHCID 2723853N-Methylhydrazinecarbothioamide

生成物 1

HCID 178482500HCID 178482500、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

A 42 g. portion of 4-methylthiosemicarbazide was reacted with 200 ml. of acetone, and then with 32 g. of pyridine and 83.6 g. of 3-trifluoromethylbenzoyl chloride. The mixture was worked-up as described in Example 1 to obtain 77.5 g. of the desired product, m.p. 111°-115°, after recrystallization from nitromethane.

後処理

  1. customto obtain 77.5 g
  2. customof the desired product, m.p. 111°-115°, after recrystallization from nitromethane

出典と根拠

ORDレコード
ord-bd0437614152434bb4e32c1135ec93de
出典データセット
uspto-grants-1982_08
特許番号
US04346225

関連ノート

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