Sodium Hydroxide → N-Methyl-N'-phenylcarbodiimide

HRID 67784

反応式

HRID 67784 の反応式
Cl.[CH3:2][NH:3][C:4](Cl)=[N:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[OH-].[Na+]>C(Cl)(Cl)Cl>[CH3:2][N:3]=[C:4]=[N:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 178484191HCID 178484191、化合物

生成物 1

HCID 138144N-Methyl-N'-phenylcarbodiimide

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

A suspension of 2.05 g of N-methyl-N'-phenylchloroformamidine hydrochloride in 8 ml of chloroform is added, at 10°-12° C., to 6 g of 20% strength sodium hydroxide solution. The mixture is stirred for 10 minutes, the organic phase is separated off, the aqueous phase is extracted twice more with chloroform and the combined organic phases are dried over K2CO3. After filtering off the desiccant, the solution is subjected to further reaction without isolating the carbodiimide.

後処理

  1. customthe organic phase is separated off
  2. extractionthe aqueous phase is extracted twice more with chloroform
  3. dry with materialthe combined organic phases are dried over K2CO3
  4. filtrationAfter filtering off the desiccant
  5. customthe solution is subjected to further reaction

出典と根拠

ORDレコード
ord-f25a5706316a4c30a4802f436981a3a1
出典データセット
uspto-grants-1982_08
特許番号
US04346088

関連ノート

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