Pyridine → 4-(2-Bromo-3-methyl-phenylcarbamoyl)-piperidine-1-carboxylic acid tert-butyl ester
反応式
[Br:21][c:22]1[c:23]([NH2:29])[cH:24][cH:25][cH:26][c:27]1[CH3:28].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:15])[OH:16])[CH2:12][CH2:13]1.[CH2:37]([Cl:38])[Cl:39].[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:40][N:41]([CH3:42])[c:43]1[cH:44][cH:45][n:46][cH:47][cH:48]1.[S:17]([Cl:18])([Cl:19])=[O:20].[cH:49]1[cH:50][cH:51][n:52][cH:53][cH:54]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:16])[NH:29][c:23]2[c:22]([Br:21])[c:27]([CH3:28])[cH:26][cH:25][cH:24]2)[CH2:12][CH2:13]1
