Glycidyl methacrylate → HCID 86744516、化合物

HRID 704056ノート

反応式

HRID 704056 の反応式
[H-].[Na+].[C:3]([C:6]1[CH:19]=[CH:18][C:17]2[S:16][C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[NH:9][C:8]=2[CH:7]=1)(=[O:5])[CH3:4].[C:20]([O:25][CH2:26][CH:27]1[O:29][CH2:28]1)(=[O:24])[C:21]([CH3:23])=[CH2:22]>O1CCCC1>[C:20]([O:25][CH2:26][CH:27]([OH:29])[CH2:28][C:7]1[C:8]2[NH:9][C:10]3[C:15](=[CH:14][CH:13]=[CH:12][CH:11]=3)[S:16][C:17]=2[CH:18]=[CH:19][C:6]=1[C:3](=[O:5])[CH3:4])(=[O:24])[C:21]([CH3:23])=[CH2:22]

参加物

5

反応物 3

HCID 7837Glycidyl methacrylateHCID 24758Sodium hydrideHCID 81131Methyl phenothiazin-2-yl ketone

生成物 1

HCID 86744516HCID 86744516、化合物収率 72.3%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒2 回

実験手順

0.20 g (0.0086 mol) of sodium hydride was added carefully to a solution of 2-acetylphenothiazine (2 g, 0.0083 mol) in 150 ml tetrahydrofuran under agitation below 5° C. A solution of glycidyl methacrylate (1.88 g, 0.013 mol) in 10 ml tetrahydrofuran was added dropwise to above solution. The reaction was kept at room temperature for 48 hours. After the solvent was removed, the residue was washed with dilute HCl and water. Dried. 2.3 g of product was obtained by recrystallization with ethyl acetate.

後処理

  1. customAfter the solvent was removed
  2. washthe residue was washed with dilute HCl and water
  3. customDried

出典と根拠

ORDレコード
ord-baf805c5eeec4a2e9733b61eafdf5c87
出典データセット
uspto-grants-1991_01
特許番号
US04985559

反応ノート

読み込み中…