Pyridine → (E)-1-[3-(4-Chlorophenoxy)phenyl]buten-3-one oxime
反応式
[Cl:1][C:2]1[CH:19]=[CH:18][C:5]([O:6][C:7]2[CH:8]=[C:9](/[CH:13]=[CH:14]/[C:15](=O)[CH3:16])[CH:10]=[CH:11][CH:12]=2)=[CH:4][CH:3]=1.Cl.[NH2:21][OH:22].N1C=CC=CC=1>CO.CCOCC>[Cl:1][C:2]1[CH:19]=[CH:18][C:5]([O:6][C:7]2[CH:8]=[C:9](/[CH:13]=[CH:14]/[C:15](=[N:21][OH:22])[CH3:16])[CH:10]=[CH:11][CH:12]=2)=[CH:4][CH:3]=1参加物
6
実験手順
The product from step (a) (19 g) and hydroxylamine hydrochloride (6.9 g) were taken up in methanol (100 ml), pyridine (20 ml) was added and the mixture stirred for 1 hour. The mixture was then stripped, redissolved in ether (200 ml), washed with 2 N aqu. HCl and satd. aqu. NaCl, dried over MgSO4, and stripped to give the desired product (20.3 g).
後処理
- washwashed with 2 N aqu
- dry with materialNaCl, dried over MgSO4
出典と根拠
- ORDレコード
- ord-8ac384bb3aa048a7a33174f8bc9c7ce6
- 出典データセット
- uspto-grants-1991_01
- 特許番号
- US04988733
反応ノート
読み込み中…