Oxalyl chloride → Dimethyl-1,3-oxazole-5-carbonyl chloride

HRID 708787

反応式

HRID 708787 の反応式
[CH3:1][C:2]1[O:3][C:4]([C:8]([OH:10])=O)=[C:5]([CH3:7])[N:6]=1.C(Cl)(=O)C([Cl:14])=O>C(Cl)Cl>[CH3:1][C:2]1[O:3][C:4]([C:8]([Cl:14])=[O:10])=[C:5]([CH3:7])[N:6]=1

参加物

4

反応物 2

HCID 65578Oxalyl chlorideHCID 1132979Dimethyl-1,3-oxazole-5-carboxylic acid

生成物 1

HCID 12336332Dimethyl-1,3-oxazole-5-carbonyl chloride

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To a stirring solution of 2,4-dimethyl-oxazole-5-carboxylic acid (30 mg) in DCM (2.0 mL), oxalyl chloride (3.0 eq) was added at room temperature. The reaction mixture was stirred for 30 minutes. Solvents were evaporated and dried under vacuo to afford 2,4-dimethyl-oxazole-5-carbonyl chloride.

後処理

  1. customSolvents were evaporated
  2. customdried under vacuo

出典と根拠

ORDレコード
ord-051aa11aea3d49acb73551ed03209563
出典データセット
uspto-grants-2015_11
特許番号
US09175003B2

関連ノート

読み込み中…