N-Iodosuccinimide → HCID 178516695、化合物
反応式
[S:1]1[C:9]2[C:4](=[N:5][CH:6]=[CH:7][C:8]=2[OH:10])[CH:3]=[CH:2]1.[I:11]N1C(=O)CCC1=O>C(#N)C>[I:11][C:7]1[C:8]([OH:10])=[C:9]2[S:1][CH:2]=[CH:3][C:4]2=[N:5][CH:6]=1参加物
4
実験手順
A mixture of thieno[3,2-b]pyridin-7-ol (from Aldrich) (0.54 g, 3.6 mmol) and N-iodosuccinimide (0.88 g, 3.9 mmol) in acetonitrile (10 mL) was heated at reflux overnight. The mixture was concentrated under reduced pressure to give the desired product which was used in the next step without further purification. LCMS calculated for C7H5INOS (M+H)+: m/z=277.9. Found: 277.8.
後処理
- temperaturewas heated
- temperatureat reflux overnight
- concentrationThe mixture was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-ea054b2c91ae4a20a0453632b40f7930
- 出典データセット
- uspto-grants-2015_11
- 特許番号
- US09181271B2
反応ノート
読み込み中…