1-Bromo-4-nitrobenzene → 4-Nitro-1,1'-biphenyl

反応式

[N+:1]([C:4]1[CH:9]=[CH:8][C:7](Br)=[CH:6][CH:5]=1)([O-:3])=[O:2].[C:11]1(B(O)O)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2]

参加物

反応物 2

HCID 114661-Bromo-4-nitrobenzene

HCID 66827Phenylboronic Acid

生成物 1

HCID 71144-Nitro-1,1'-biphenyl

実験手順

4-Nitro-bromobenzene and phenyl boronic acid were reacted as described in Example 6. The catalyst was recovered by filtration, washed and dried (as described in Example 1). This process was then repeated 4 times with fresh reagents and the recycled catalyst. The yields of isolated 4-Nitrobiphenyl were as follows:

後処理

filtrationThe catalyst was recovered by filtration
washwashed
customdried (as described in Example 1)

出典と根拠

ORDレコード: ord-05b04c0b57cb4631982c99303f558e8c
出典データセット: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08828902B2

反応ノート

読み込み中…

参加物