L-Phenylalanine → Phenylalanine butyramide

反応式

[NH2:1][C@H:2]([C:10]([OH:12])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[C:13]([O:18]C(=O)CCC)(=O)[CH2:14][CH2:15][CH3:16]>>[C:13]([NH2:1])(=[O:18])[CH2:14][CH2:15][CH3:16].[NH2:1][C@H:2]([C:10]([OH:12])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

参加物

反応物 2

HCID 6140L-Phenylalanine

HCID 7798Butyric anhydride

生成物 1

HCID 68631493Phenylalanine butyramide

反応条件

温度: 100 °C

実験手順

5 g of phenylalanine was added to 20 mL of butyric anhydride and the resulting mixture heated to about 100° C. for about 3 h. Excess butyric anhydride was then removed under reduced pressure to provide a solid residue that was recrystallized from ethanol to provide phenylalanine butyramide.

後処理

customExcess butyric anhydride was then removed under reduced pressure
customto provide a solid residue that
customwas recrystallized from ethanol

出典と根拠

ORDレコード: ord-3e84eb0ed57b475cbbdee34bf3c5aaeb
出典データセット: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08828960B2

反応ノート

読み込み中…

参加物