Methyl vinyl sulfone → 1-(2-Methanesulfonyl-ethyl)-4-(4-nitro-phenyl)-[1,4]diazepane

HRID 72208

反応式

HRID 72208 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:16][CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:17][S:18]([CH:21]=[CH2:22])(=[O:20])=[O:19]>CO>[CH3:17][S:18]([CH2:21][CH2:22][N:13]1[CH2:14][CH2:15][CH2:16][N:10]([C:7]2[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=2)[CH2:11][CH2:12]1)(=[O:20])=[O:19]

参加物

4

反応物 2

HCID 19354Methyl vinyl sulfoneHCID 50559501-(4-Nitrophenyl)-1,4-diazepane

生成物 1

HCID 689796131-(2-Methanesulfonyl-ethyl)-4-(4-nitro-phenyl)-[1,4]diazepane

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

A mixture of 1-(4-Nitro-phenyl)-[1,4]diazepane (4.90 g), Methansulfonyl-ethene (2.35 g) and Methanol (50 mL) was stirred for 2 h at room temperature. The volatiles were removed in vacuo. The product with the molecular weight of 327.40 (C14H21N3O4S) was obtained in this way; MS (ESI): 328 (M+H+).

後処理

  1. customThe volatiles were removed in vacuo
  2. customThe product with the molecular weight of 327.40 (C14H21N3O4S) was obtained in this way

出典と根拠

ORDレコード
ord-f675f3baab6544c48293dbeb4ed82bcd
出典データセット
uspto-grants-2014_09
特許番号
US08828991B2

関連ノート

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