Thioacetamide → HCID 178488187、化合物

HRID 722199

反応式

HRID 722199 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12]=1[N+:13]([O-:15])=[O:14])[C:6]([NH:8][NH2:9])=O.[C:16]([NH2:19])(=S)[CH3:17]>N1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:6]2[NH:19][C:16]([CH3:17])=[N:9][N:8]=2)[CH:10]=[CH:11][C:12]=1[N+:13]([O-:15])=[O:14]

参加物

4

反応物 2

HCID 2723949ThioacetamideHCID 218838753-Methoxy-4-nitrobenzohydrazide

生成物 1

HCID 178488187HCID 178488187、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

反応条件

温度
95 °C

実験手順

The mixture consisting of 590 mg g of 3-methoxy-4-nitrobenzoic hydrazide, 6 ml of pyridine and 210 mg of thioacetamide was heated to 95° C. for 2 hours. After cooling, the volatile fractions were removed under reduced pressure at 40° C. and the residue was subjected to column chromatography purification (silica gel, solvent: 95:5 dichloromethane:methanol)

後処理

  1. temperatureAfter cooling
  2. customthe volatile fractions were removed under reduced pressure at 40° C.
  3. customthe residue was subjected to column chromatography purification (silica gel, solvent: 95:5 dichloromethane:methanol)

出典と根拠

ORDレコード
ord-1b016a8858ed40a18d46df865caf42b4
出典データセット
uspto-grants-2006_11
特許番号
US07138414B2

関連ノート

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