Pyridine → 4-Methyl-N-(oxo-lambda~4~-sulfanylidene)benzamide
反応式
[C:1]1([CH3:10])[CH:6]=[CH:5][C:4]([C:7]([NH2:9])=[O:8])=[CH:3][CH:2]=1.N1C=CC=CC=1.[S:17](Cl)(Cl)=[O:18]>CCOCC>[S:17](=[N:9][C:7]([C:4]1[CH:5]=[CH:6][C:1]([CH3:10])=[CH:2][CH:3]=1)=[O:8])=[O:18]参加物
5
実験手順
p-Toluamide (76 g) and pyridine (95.5 ml) were initially charged in dry ether (600 ml) and, while cooling with ice, thionyl chloride (70.2 g) in ether (200 ml) was added dropwise. The mixture was stirred at room temperature overnight. With exclusion of moisture, the pyridine hydrochloride was then filtered off and washed with ether (100 ml). The solution was concentrated under reduced pressure and the residue (83.5 g) was used without further purification.
後処理
- additionwas added dropwise
- filtrationWith exclusion of moisture, the pyridine hydrochloride was then filtered off
- washwashed with ether (100 ml)
- concentrationThe solution was concentrated under reduced pressure
- customthe residue (83.5 g) was used without further purification
出典と根拠
- ORDレコード
- ord-40888b505acd4683b7f2770905b7cad1
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08828995B2
反応ノート
読み込み中…