Hydrochloric Acid → N-tosyl-bis(2-tosyloxy propyl) amine

HRID 728630

反応式

HRID 728630 の反応式
[CH3:1][CH:2]([OH:9])[CH2:3][NH:4][CH2:5][CH:6]([OH:8])[CH3:7].[S:10](Cl)([C:13]1[CH:19]=[CH:18][C:16]([CH3:17])=[CH:15][CH:14]=1)(=[O:12])=[O:11].[OH2:21].Cl>N1C=CC=CC=1>[S:10]([N:4]([CH2:5][CH:6]([O:8][S:10]([C:13]1[CH:19]=[CH:18][C:16]([CH3:17])=[CH:15][CH:14]=1)(=[O:12])=[O:11])[CH3:7])[CH2:3][CH:2]([O:9][S:10]([C:13]1[CH:19]=[CH:18][C:16]([CH3:17])=[CH:15][CH:14]=1)(=[O:11])=[O:21])[CH3:1])([C:13]1[CH:19]=[CH:18][C:16]([CH3:17])=[CH:15][CH:14]=1)(=[O:12])=[O:11]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 73974-Toluenesulfonyl chlorideHCID 8086Diisopropanolamine

生成物 1

HCID 17769785N-tosyl-bis(2-tosyloxy propyl) amine

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒2 回

実験手順

A solution of 53.2 g (0.4 mole) of diiso-propanolamine in 50 cm3 of pyridine is added dropwise with cooling to a solution of 248 g (1.3 mole) of tosyl chloride in 200 cm3 of pyridine at 0° C. so that the temperature is maintained between 0° and 5° C. The mixture is left at this temperature for 72 h. It is then poured into 2 l of water plus ice and 250 cm3 of concentrated hydrochloric acid.

後処理

  1. temperatureis maintained between 0° and 5° C

出典と根拠

ORDレコード
ord-96d9d9e990a04f49bfd810ca007ce619
出典データセット
uspto-grants-1991_09
特許番号
US05049667

関連ノート

読み込み中…