m-Chloroperbenzoic acid → 2-[6(n-Pentylsulfinyl)-2-pyridyl]-4H-1,3-benzothiazine-4-on e

HRID 748224ノート

反応式

HRID 748224 の反応式
[CH2:1]([S:6][C:7]1[N:12]=[C:11]([C:13]2[S:14][C:15]3[CH:23]=[CH:22][CH:21]=[CH:20][C:16]=3[C:17](=[O:19])[N:18]=2)[CH:10]=[CH:9][CH:8]=1)[CH2:2][CH2:3][CH2:4][CH3:5].ClC1C=CC=C(C(OO)=[O:32])C=1>C(Cl)(Cl)Cl>[CH2:1]([S:6]([C:7]1[N:12]=[C:11]([C:13]2[S:14][C:15]3[CH:23]=[CH:22][CH:21]=[CH:20][C:16]=3[C:17](=[O:19])[N:18]=2)[CH:10]=[CH:9][CH:8]=1)=[O:32])[CH2:2][CH2:3][CH2:4][CH3:5]

参加物

4

反応物 2

HCID 70297m-Chloroperbenzoic acidHCID 597502962-[6-(Pentylthio)-2-pyridyl]-4H-1,3-benzothiazine-4-one

生成物 1

HCID 597501432-[6(n-Pentylsulfinyl)-2-pyridyl]-4H-1,3-benzothiazine-4-on e収率 48%

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒2 回

実験手順

2-[6-(n-Pentylthio)-2-pyridyl]-4H-1,3-benzothiazine-4-one (0.15 g, 0.44 mmol) was dissolved in chloroform (50 ml), and a solution of 3-chloroperbenzoic acid (ca. 77%, 0.10 g, 0.46 mmol) in chloroform (10 ml) was added dropwise thereto. The reaction mixture was stirred at room temperature for 1 hr. The solvent was evaporated, and the residue was recrystallized from ethanol to give the titled compound (0.075 g, 48%) as white crystals.

後処理

  1. customThe solvent was evaporated
  2. customthe residue was recrystallized from ethanol

出典と根拠

ORDレコード
ord-44a318ebc4944d33ad0226edc709bc89
出典データセット
uspto-grants-2008_07
特許番号
US07399759B2

反応ノート

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