Pyridine → 3,5-dimethyl-1-m-tolyl-1H-pyrazole-4-carboxylic acid ethyl ester
反応式
Cl.[C:2]1([CH3:10])[CH:7]=[CH:6][CH:5]=[C:4]([NH:8][NH2:9])[CH:3]=1.[CH2:11]([O:13][C:14](=[O:22])[CH:15]([C:19](=O)[CH3:20])[C:16](=O)[CH3:17])[CH3:12].N1C=CC=CC=1>C(O)C>[CH2:11]([O:13][C:14]([C:15]1[C:16]([CH3:17])=[N:9][N:8]([C:4]2[CH:3]=[C:2]([CH3:10])[CH:7]=[CH:6][CH:5]=2)[C:19]=1[CH3:20])=[O:22])[CH3:12]参加物
5
実験手順
Similar to Example 1, equimolar amounts of m-tolylhydrazine hydrochloride and 2-acetyl-3-oxo-butyric acid ethyl ester were combined in a solution of a 50% pyridine in ethanol. The resulting oil was purified by flash chromatography to yield the named product as a solid (m.p. 46.5° C.–47.5° C.).
後処理
- customThe resulting oil was purified by flash chromatography
出典と根拠
- ORDレコード
- ord-10ff9f3ebf424ef1bf07a369dc0fa429
- 出典データセット
- uspto-grants-2006_08
- 特許番号
- US07087634B2
反応ノート
読み込み中…