Methyl iodide → 7-Methyl-8-oxo-2H,8H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-7-ium iodide

HRID 838929ノート

反応式

HRID 838929 の反応式
[CH:1]1[CH:2]=[CH:3][C:4]2[C:14](=[O:15])[C:13]3[C:8]4[C:9](=[CH:16][C:17]5[O:21][CH2:20][O:19][C:18]=5[C:7]=4[C:5]=2[CH:6]=1)[CH:10]=[CH:11][N:12]=3.[I:22][CH3:23]>C(Cl)(Cl)Cl>[CH3:23][N+:12]1[CH:11]=[CH:10][C:9]2[C:8]3=[C:7]([C:18]4[O:19][CH2:20][O:21][C:17]=4[CH:16]=2)[C:5]2[C:4]([C:14](=[O:15])[C:13]=13)=[CH:3][CH:2]=[CH:1][CH:6]=2.[I-:22]

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 10144Liriodenine2 回

生成物 1

HCID 1227727-Methyl-8-oxo-2H,8H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-7-ium iodide

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

Liriodenine methiodide was prepared from the liriodenine isolated in accordance with Example 1. A 2.71 gm sample of liriodenine was reflexed in 30 ml of chloroform and then 10 ml of iodomethane was added. After 24 hours at reflux, the solution was cooled, excess iodomethane removed, and the red crystals filtered. Crystallization from methanol yielded 2.24 gm liriodenine methiodide, mp 235 d.

後処理

  1. customisolated in accordance with Example 1
  2. temperatureAfter 24 hours at reflux
  3. temperaturethe solution was cooled
  4. customexcess iodomethane removed
  5. filtrationthe red crystals filtered
  6. customCrystallization from methanol

出典と根拠

ORDレコード
ord-b406a0fd906441c69e7be19269da442f
出典データセット
uspto-grants-1978_06
特許番号
US04093717

反応ノート

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