Ammonia → 2-Ethynylnaphthalene

HRID 840016

反応式

HRID 840016 の反応式
[CH:1]([C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1)=[CH2:2].C(Cl)(Cl)Cl.[Br].BrBr.N.[NH2-].[Na+]>C(Cl)(Cl)Cl>[C:1]([C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1)#[CH:2]

参加物

7

反応物 5

HCID 222AmmoniaHCID 132302-VinylnaphthaleneHCID 24408BromineHCID 24533Sodium amideHCID 178478473HCID 178478473、化合物

生成物 1

HCID 1150172-Ethynylnaphthalene

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

To a mixture of 15.5 g. of 2-vinylnaphthalene and 300 ml. of chloroform, a 5% bromine chloroform solution is added at -10° C until the bromine color persists. The mixture is then added to 200 ml. of ammonia containing 15 g. of sodium amide. The mixture is allowed to evaporate; the residue is extracted with diethyl ether. The extracts are combined, washed to neutrality with water, dried, and evaporated to yield 2-ethynylnaphthalene.

後処理

  1. additionTo a mixture of 15.5 g
  2. additionThe mixture is then added to 200 ml
  3. customto evaporate
  4. extractionthe residue is extracted with diethyl ether
  5. washwashed
  6. customdried
  7. customevaporated

出典と根拠

ORDレコード
ord-57774d12659e40cbb6a9f98b4491b09a
出典データセット
uspto-grants-1978_06
特許番号
US04097674

関連ノート

読み込み中…