HCID 14054010、化合物 → N-(2-Aminophenyl)-4-(2-methylpropanamido)benzamide
反応式
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11](=[O:24])[C:12]1[CH:17]=[CH:16][C:15]([NH:18][C:19](=[O:23])[CH:20]([CH3:22])[CH3:21])=[CH:14][CH:13]=1)([O-])=O>O1CCCC1.[Pd]>[C:19]([NH:18][C:15]1[CH:16]=[CH:17][C:12]([C:11]([NH:10][C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[NH2:1])=[O:24])=[CH:13][CH:14]=1)(=[O:23])[CH:20]([CH3:22])[CH3:21]参加物
4
実験手順
13.1 g (40 mMole) N-(2'-nitrophenyl)-4-isobutyrylaminobenzamide are hydrogenated under standard conditions in 400 mL tetrahydrofuran in the presence of 10% palladium charcoal. After concentrating the solvent to 120 mL, the precipitated crystals are filtered off with suction. Yield 10.2 g (86% of theory); m.p. 247.6° C.
後処理
- concentrationAfter concentrating the solvent to 120 mL