Benzaldehyde → 1-Nitro-2-phenylethane

反応式

[N+:1](/[CH:4]=[CH:5]/[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)([O-:3])=[O:2].C(=O)C1C=CC=CC=1.NC1C=CC=CC=1N>>[N+:1]([CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)([O-:3])=[O:2]

参加物

反応物 3

HCID 240Benzaldehyde

HCID 7243O-Phenylenediamine

HCID 5284459beta-nitrostyrene, (E)-

生成物 1

HCID 802081-Nitro-2-phenylethane収率 95%

実験手順

Example 219 A) trans-b-Nitrostyrene (63.0 g, 0.42 mole) was reacted with benzaldehyde (53.4 g, 0.5 mole) and 1,2-diaminobenzene (54.4 g, 0.5 mole) according to the procedure of Chikashita et. al. (Synth. Commun. 1985, 15 (6), 527) to yield (2-nitroethyl)benzene (60.0 g, 95%) as a yellow oil.

出典と根拠

ORDレコード: ord-fa6a597758a845449a7c3c11fe37506c
出典データセット: uspto-grants-2000_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06011028

反応ノート

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