Methyl triflate → 1-Methyl-1H-indole-5-carboxylic acid

HRID 858184

反応式

HRID 858184 の反応式
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([C:10]([OH:12])=[O:11])=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.F[C:14](F)(F)S(OC)(=O)=O>CN(C=O)C>[CH3:14][N:1]1[C:9]2[C:4](=[CH:5][C:6]([C:10]([OH:12])=[O:11])=[CH:7][CH:8]=2)[CH:3]=[CH:2]1

参加物

4

反応物 2

HCID 9526Methyl triflateHCID 742801H-Indole-5-Carboxylic Acid

生成物 1

HCID 70156011-Methyl-1H-indole-5-carboxylic acid

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

0.1 g of indol-5-carboxylic acid was mixed with 2 equivalents of methyl trifluoromethane sulfonate in 1 ml DMF at room temperature. After 5 h the solvent was evaporated and 1H-NMR was recorded:

後処理

  1. customAfter 5 h the solvent was evaporated

出典と根拠

ORDレコード
ord-a0d26f19bf7a4baf960f448a6e4bd646
出典データセット
uspto-grants-2006_12
特許番号
US07148243B2

関連ノート

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