Sodium Carbonate → 3-Allyl-4-hydroxybenzamidoxime
反応式
[CH2:1]([C:4]1[CH:9]=[C:8]([C:10]#[N:11])[CH:7]=[CH:6][C:5]=1[OH:12])[CH:2]=[CH2:3].Cl.[NH2:14][OH:15].C(=O)([O-])[O-].[Na+].[Na+]>C(O)C>[CH2:1]([C:4]1[CH:9]=[C:8]([CH:7]=[CH:6][C:5]=1[OH:12])[C:10](=[N:14][OH:15])[NH2:11])[CH:2]=[CH2:3]参加物
5
実験手順
A solution of 2-allyl-4-cyanophenol (5.5 g), hydroxylamine hydrochloride (8.5 g) and sodium carbonate (6.1 g) in aqueous ethanol was heated at reflux for 3 hours. The solution was cooled to ambient temperature and the ethanol was removed by evaporation. The solid was collected by filtration, dissolved in ethanol and the solution was filtered. The filtrate was evaporated and the residual solid was triturated with hexane to give 3-allyl-4-hydroxybenzamidoxime as a solid (5.5 g), m.p. 144° C.
後処理
- temperatureat reflux for 3 hours
- customthe ethanol was removed by evaporation
- filtrationThe solid was collected by filtration
- dissolutiondissolved in ethanol
- filtrationthe solution was filtered
- customThe filtrate was evaporated
- customthe residual solid was triturated with hexane
出典と根拠
- ORDレコード
- ord-fa68b737bee540c3a23ea665129b0621
- 出典データセット
- uspto-grants-1998_02
- 特許番号
- US05714496
反応ノート
読み込み中…