2-(2-Nitrophenoxy)acetamide → HCID 20283931、化合物
反応式
[C:1]([CH2:4][O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[N+:12]([O-])=O)(=[O:3])[NH2:2]>O1CCCC1.[Pd]>[C:1]([CH2:4][O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[NH2:12])(=[O:3])[NH2:2]参加物
4
実験手順
2.0 g of 2-(carbamoylmethoxy)nitrobenzene are hydrogenated in the presence of 100 mg of palladium-on-charcoal (10% of Pd) in 50 ml of tetrahydrofuran at room temperature under normal pressure for 2 h. The reaction mixture is filtered over Hyflo® and concentrated. 2-(Carbamoylmethoxy)aniline is obtained as white crystals: mp 117° C.; Rf (O)=0.36; FAB-MS: (M+H)+ =167; anal. calc. for C8H10N2O2 : C57.82%, H6.07%, N16.86%; found C57.71%, H6.04%, N16.87%.
後処理
- filtrationThe reaction mixture is filtered over Hyflo®
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-1f944dd6fabf49d19b43437021e8e25b
- 出典データセット
- uspto-grants-1998_02
- 特許番号
- US05719141
反応ノート
読み込み中…