Water → 3-Formylchromone

HRID 866339ノート

反応式

HRID 866339 の反応式
[OH:1][CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[O:5][CH:4]=1.O>[N+]([O-])(O)=O>[CH:2]([C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[O:5][CH:4]=1)=[O:1]

参加物

4

反応物 2

HCID 962WaterHCID 113557983-(hydroxymethyl)-4H-chromen-4-one

生成物 1

HCID 871123-Formylchromone

試薬・触媒・溶媒 1

HCID 944Nitric Acid溶媒

反応条件

温度
25 °C

実験手順

A quantity of 35.2 g. (0.2 mole) of 3-(hydroxymethyl)chromone is dissolved in 250 ml of concentrated nitric acid with stirring at 25° C. There is no initial heat of reaction. The temperature gradually rises to 30° C over the next several minutes and is kept there for about five minutes with ice-acetone bath cooling. Water, 600 ml, is added to the reaction solution. The separated, pale yellow solid is filtered, washed well with water and dried to give 25 g. of crude aldehyde melting at 145°-148°.

後処理

  1. temperatureno initial heat of reaction
  2. customgradually rises to 30° C over the next several minutes
  3. temperaturecooling
  4. filtrationThe separated, pale yellow solid is filtered
  5. washwashed well with water
  6. customdried
  7. customto give 25 g

出典と根拠

ORDレコード
ord-f9cb4f5f974a41769ac715fee52a55f0
出典データセット
uspto-grants-1978_07
特許番号
US04098799

反応ノート

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