HCID 20318584、化合物 → 5-(2-Amino-1-hydroxyethyl)-o-anisamide

HRID 866777

反応式

HRID 866777 の反応式
C([N:8](CC1C=CC=CC=1)[CH2:9][C:10]([C:12]1[CH:20]=[C:16]([C:17]([NH2:19])=[O:18])[C:15]([O:21][CH3:22])=[CH:14][CH:13]=1)=[O:11])C1C=CC=CC=1.[H][H]>O1CCCC1.C(O)C.[Pd]>[NH2:8][CH2:9][CH:10]([C:12]1[CH:20]=[C:16]([C:17]([NH2:19])=[O:18])[C:15]([O:21][CH3:22])=[CH:14][CH:13]=1)[OH:11]

参加物

6

反応物 2

HCID 20318584HCID 20318584、化合物HCID 178418361HCID 178418361、化合物

生成物 1

HCID 203185835-(2-Amino-1-hydroxyethyl)-o-anisamide

試薬・触媒・溶媒 3

HCID 23938Palladium触媒HCID 702Ethanol溶媒2 回HCID 8028Tetrahydrofuran溶媒

実験手順

A solution of 5-(N,N-dibenzylglycyl)-o-anisamide (3.88g) in tetrahydrofuran (25 ml) and ethanol (125ml) was added to a pre-reduced suspension of 10% Pd/C (1.0g) in ethanol (25 ml). Uptake of hydrogen ceased within 14 hours. The catalyst was filtered off and the solvent evaporated under reduced pressure to leave 5-(2-amino-1-hydroxyethyl)-o-anisamide as a colourless gum.

後処理

  1. filtrationThe catalyst was filtered off
  2. customthe solvent evaporated under reduced pressure

出典と根拠

ORDレコード
ord-4f0d162cc99e46d8bdd5aa4995cc500b
出典データセット
uspto-grants-1978_07
特許番号
US04101579

関連ノート

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