Allyl chloride → 1-(3,3-Dimethylcyclohexyl)ethanone

HRID 867153

反応式

HRID 867153 の反応式
[C:1]([CH:4]1[CH2:9][CH2:8][CH2:7][C:6]([CH3:11])([CH3:10])[CH2:5]1)(=[O:3])[CH3:2].[OH-].[Na+].[CH2:14](Cl)[CH:15]=[CH2:16].[CH2:18](N(CC)CC)[CH3:19]>O>[C:1]([CH:4]1[CH2:9][CH2:8][CH2:7][C:6]([CH3:11])([CH3:10])[CH2:5]1)(=[O:3])[CH3:2].[C:1]([C:4]1([CH2:14][CH:15]=[CH:16][CH2:18][CH3:19])[CH2:9][CH2:8][CH2:7][C:6]([CH3:11])([CH3:10])[CH2:5]1)(=[O:3])[CH3:2].[CH3:10][C:6]1([CH3:11])[CH2:7][CH2:8][CH2:9][CH:4]([C:1](=[O:3])[CH2:2][CH2:16][CH:15]=[CH2:14])[CH2:5]1

参加物

8

反応物 4

HCID 7850Allyl chlorideHCID 8471TriethylamineHCID 14798Sodium HydroxideHCID 913881-(3,3-Dimethylcyclohexyl)ethanone

生成物 3

HCID 913881-(3,3-Dimethylcyclohexyl)ethanoneHCID 64534231-(3,3-Dimethylcyclohexyl)-pent-4-en-1-oneHCID 537246071-Acetyl-3,3-dimethyl-1-(2-pentenyl) cyclohexane

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A mixture of 1-acetyl-3,3-dimethylcyclohexane (156 grams, 1 mole), sodium hydroxide (60 grams, 1.5 moles), allyl chloride (114 grams, 1.5 moles) and triethylamine (10 grams) is stirred and heated at 80°-84° C. for 12 hours. The reaction mass is cooled to room temperature. Water is added with stirring, and the aqueous layer is discarded. The organic layer is distilled to afford 119 grams of 1-acetyl-3,3-dimethylcyclohexane, 31 grams of 1-acetyl-3,3-dimethyl-1-(2-pentenyl) cyclohexane, and 5 grams of 3,3-dimethyl-1-(4-pentenoyl) cyclohexane.

後処理

  1. temperatureheated at 80°-84° C. for 12 hours
  2. stirringwith stirring
  3. distillationThe organic layer is distilled

出典と根拠

ORDレコード
ord-eea4779a8076450b860971bd9ec322b9
出典データセット
uspto-grants-1978_07
特許番号
US04102928

関連ノート

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