Dimethylamine → 2,4-Diamino-6-(3-dimethylsulfamylphenyl)-s-triazine

HRID 867159

反応式

HRID 867159 の反応式
[CH:1]1[CH:2]=[CH:3][C:4]([C:7]2[N:8]=[C:9]([NH2:14])[N:10]=[C:11]([NH2:13])[N:12]=2)=[CH:5][CH:6]=1.[CH3:15][NH:16][CH3:17].O1CCOCC1.Cl[S:25](O)(=[O:27])=[O:26]>>[NH2:13][C:11]1[N:10]=[C:9]([NH2:14])[N:8]=[C:7]([C:4]2[CH:3]=[CH:2][CH:1]=[C:6]([S:25](=[O:27])(=[O:26])[N:16]([CH3:17])[CH3:15])[CH:5]=2)[N:12]=1

参加物

5

反応物 4

HCID 674DimethylamineHCID 7064BenzoguanamineHCID 24638Chlorosulfonic acidHCID 312751,4-Dioxane

生成物 1

HCID 203177202,4-Diamino-6-(3-dimethylsulfamylphenyl)-s-triazine

実験手順

5.7 g of benzoguanamine is heated in 12 g of chlorosulfonic acid at 130° to 140° C. for 4 hours. After cooling, the reaction mixture is added dropwise into a mixture of 40 ml of 40% aqueous dimethylamine and 50 ml of dioxane under agitation and ice cooling, and after one hour agitation, the mixture is evaporated to dryness under vacuum. Thereafter, water is added to the mixture and the separated crystals are filtered out and recrystallized from dioxane. Melting point: 250°-251° C.; yield: 8.8 g.

後処理

  1. temperatureAfter cooling
  2. customthe mixture is evaporated to dryness under vacuum
  3. additionThereafter, water is added to the mixture
  4. filtrationthe separated crystals are filtered out
  5. customrecrystallized from dioxane

出典と根拠

ORDレコード
ord-d5d29645d7544dbdb4d1de01a43c75c8
出典データセット
uspto-grants-1978_07
特許番号
US04103009

関連ノート

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