Water → HCID 16679760、化合物

反応式

[OH-:1].[Na+].O.[C:4]([S:8][CH2:9][C:10]1([CH3:17])[NH:14][C:13](=[O:15])[NH:12][C:11]1=[O:16])([CH3:7])([CH3:6])[CH3:5]>C(#N)C>[C:13]([NH:14][C@:10]([CH3:17])([C:11]([OH:1])=[O:16])[CH2:9][S:8][C:4]([CH3:7])([CH3:6])[CH3:5])(=[O:15])[NH2:12]

参加物

実験手順

First, sodium hydroxide and water were added to 5-tert-butylthiomethyl-5-methylhydantoin, and the resultant mixture was heated to a predetermined temperature and stirred. The reaction solution was analyzed by HPLC (column: COSMOSIL 5C18-AR (produced by Nacalai Tesque Inc.), mobile phase: acetonitrile/10 mM aqueous potassium dihydrogen phosphate solution=30/70, flow rate: 1.0 ml/min, detection wavelength: 210 nm, column temperature: 40° C.) to determine the yield of the title compound. The results are shown in Table 1.