Acetic Acid → HCID 86650351、化合物

HRID 885782ノート

反応式

HRID 885782 の反応式
Br[CH2:2][C:3]([O:11][CH3:12])=[CH:4][C:5](=[O:10])[C:6]([F:9])([F:8])[F:7].[C:13]([O-:16])(=[O:15])[CH3:14].[K+].C(O)(=O)C>[Br-].C([N+](CCCC)(CCCC)CCCC)CCC.C(#N)C>[C:13]([O:16][CH2:2][C:3]([O:11][CH3:12])=[CH:4][C:5](=[O:10])[C:6]([F:9])([F:8])[F:7])(=[O:15])[CH3:14]

参加物

6

反応物 3

HCID 176Acetic AcidHCID 517044Potassium AcetateHCID 5153113CID 5153113

生成物 1

HCID 86650351HCID 86650351、化合物

試薬・触媒・溶媒 2

HCID 74236Tetrabutylammonium Bromide触媒HCID 6342Acetonitrile溶媒

実験手順

24.8 g (0.1 mol) of 5-bromo-1,1,1-trifluoro-4-methoxypent-3-en-2-one, 20 g of potassium acetate, 5 g of tetrabutylammonium bromide and 8 g of acetic acid were stirred in 300 ml of acetonitrile at 40° C. for 20 h. The precipitate was filtered off and the solvent was removed completely under reduced pressure.

後処理

  1. filtrationThe precipitate was filtered off
  2. customthe solvent was removed completely under reduced pressure

出典と根拠

ORDレコード
ord-7f330ea03c0e44b48d5c4db88bd3b0d1
出典データセット
uspto-grants-2012_08
特許番号
US08242313B2

反応ノート

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